Dr. Assunta Giordano, Ph.D.
ORCiD: https://orcid.org/0000-0001-8139-407X
Scopus: https://www.scopus.com/authid/detail.uri?authorId=35617957500
Current position:
Permanent Researcher at the Institute of Biomolecular Chemistry (ICB) Consiglio Nazionale delle Ricerche (CNR).
Background:
PhD in Chemistry at the University of Salerno, Italy.
Master Degree in Chemistry at the University of Salerno, Italy.
Research and awards:
My research activity of Dr. Assunta Giordano was initially carried out at the Department of Organic Chemistry, University of Salerno, where I completed my PhD and spent two years as a postdoctoral fellow. In this period my work was focused on the synthesis of marine natural products having a biological activity. The work was specially centered on the study of new methodologies for the enantioselective synthesis of organic compounds. After moving to the Institute of Biomolecular Chemistry (National Research Council), my interests shifted on the following topics:
- application of enzymes in organic synthesis (in glycosyl hydrolase and alcohol dehydrogenase);
- chemotaxonomic analysis of extremophilic batteries;
- structural characterization of polysaccharides and glycoproteins from bacteria and archaea.
From 2013 to date I am associate researcher at the department of Pharmacy of the University of Salerno. In the last years, my research topics include the development of synthetic compounds with anti-inflammatory and antitumor activities. These research activities concern the design, synthesis and study of the biological activity of inhibitors of microsomal prostaglandin E synthase-1 (mPGES-1) and soluble epoxy hydrolase (sHE), all involved in the inflammatory cascade, and the synthesis of molecules that modulate the function of proteins involved in epigenetic signalling, (BRD9 and JMJD3).